DACH1 Rabbit anti-Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523483
DescriptionDachshund homolog 1 belongs to the DACH/Dachshund family. It is a transcription factor involved in the regulation of organogenesis. DACH1 plays a role in retinal and pituitary precursor cell proliferation. It is reported to be expressed in breast cancer cell lines and to inhibit transforming growth factor-beta (TGF-beta)-induced apoptosis. DACH1 repressed TGF-beta induction of AP-1 and Smad signaling in gene reporter assays and repressed endogenous TGF-beta-responsive genes by microarray analyses. DACH1 participates in the negative regulation of TGF-beta signaling by interacting with NCoR and Smad4. Mouse DACH1 protein was immunolocalized to specific cell types within the developing kidneys, eyes, cochleae, and limb buds.
|Synthetic peptide (474 SPPSRVETSVIKERVPDS 491) of Dach1 protein.|
|Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|RP11-512J14.1, DACH, dachshund homolog 1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100065685, 13134, 1602, 373935, 485489, 537184|
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