DAP12 Polyclonal Antibody, Invitrogen™

DAP12 Antibody, PA1-12701, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Manufacturer: Invitrogen PA112701

Catalog No. 01-674-839

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    Formulation 100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
    Applications Immunoprecipitation,Western Blot
    Gene Accession No. O43914, O54885
    Gene Symbols TYROBP
    Species Reactivity Human, Mouse
    Storage Requirements Avoid Freeze/Thaw Cycles
    Gene ID (Entrez) 22177, 7305
    Immunogen Recombinant DAP12 protein.
    Isotype IgG
    Cross Reactivity Human,Mouse
    Antigen DAP12
    Format Purified
    Host Species Rabbit
    Quantity 100μg
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Conjugate Unlabeled

    DAP12 Antibody, PA1-12701, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

    DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
    Host Species: Rabbit
    Cross Reactivity: Human, Mouse
    Isotype: IgG
    Immunogen: Recombinant DAP12 protein.
    Formulation: 100µg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
    Synonyms: TYROBP, KARAP, PLOSL
    Uniprot Accession: O43914, O54885
    Entrez GeneID: 22177, 7305
    Gene Symbol: TYROBP
    A suggested positive control for this product is NKp44 positive cells.

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