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DAP12 Polyclonal Antibody, Invitrogen™

DAP12 Antibody, PA1-12701, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Manufacturer:  Invitrogen PA112701

Catalog No. 01-674-839


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Specifications

Description

DAP12 Antibody, PA1-12701, from Invitrogen. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Recombinant DAP12 protein.
Formulation: 100µg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Synonyms: TYROBP, KARAP, PLOSL
Uniprot Accession: O43914, O54885
Entrez GeneID: 22177, 7305
Gene Symbol: TYROBP
A suggested positive control for this product is NKp44 positive cells.
Description & Specifications

Specifications

DAP12
Unlabeled
O43914, O54885
TYROBP, KARAP, PLOSL
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Human,Murine
Immunoprecipitation,Western Blot
100μg purified antibody (1mg/mL) in PBS and 0.08% sodium azide
Purified
TYROBP
Recombinant DAP12 protein.
100μg
Primary
22177, 7305
Promotions

Promotions

  • Purchase any three Invitrogen™ Antibodies and receive a fourth antibody at no additional cost. This is an NLSU exclusive offer. You must apply and qualify for the program to be eligible.

    06-30-2018

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