DAZL Rabbit anti-Bovine, Canine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523152
PA5-23152 targets DAZL in WB applications and shows reactivity with Bovine, Canine, Human, mouse, new world monkey and chimpanzee samples.Protein expression pattern show that DAZL is involved in mitosis and meiosis of human germ cell. The DAZL gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females .The protein is expressed in germ cells of diverse mammalian species. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In humans, DAZL is expressed in primordial germ cells, adult testis, and the ovary. It plays a central role during spermatogenesis. Defects in DAZL may cause infertility due to severe oligozoospermia (az) and non obstructive azoospermia. The concentrations of DAZL transcripts were lower in men with spermatogenic failure. Drosophila and mouse mutants that have lost DAZ homologous gene function found to be azoospermic, just as with human azoospermia DAZ. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome.
|whole serum with 50% glycerol and 0.025% sodium azide|
|DAZH, DAZL1, DAZLA, SPGYLA, DAZ homolog, DAZ-like autosomal, SPGY-like-autosomal, deleted in azoospermia-like 1, germline specific RNA binding protein, spermatogenesis gene on the Y-like autosomal|
|Bovine, Canine, Human, Mouse, Non-human primate|
|Synthetic peptide (50 RMDETEIRSFFARYG 64) of DAZL protein.|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|13164, 1618, 477055, 530116|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok