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RhoBTB2 Mouse anti-Human, Clone: 2G6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521429

Catalog No. PIMA521429


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Description

Description

Peptide Sequence: TISAHKPLLI SSCDWMAAMF GGPFVESSTR EVVFPYTSKS CMRAVLEYLY TGMFTSSPDL DDMKLIILAN RLCLPHLVAL TEQYTVTGLM EATQMMVDID GDVLVFLELA

RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues. RHOBTB1 is thought to play a role in GTPase-mediated signaling and may participate in organization of the Actin filament system. Additionally, RHOBTB1 expression is decreased in head and neck carcinomas, suggesting a possible role for RHOBTB1 as a tumor suppressor.
Specifications

Specifications

RhoBTB2
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q9BYZ6
Rho-related BTB domain-containing protein 2, Deleted in breast cancer 2 gene protein, p83, RHOBTB2, DBC2, KIAA0717, Rho-related BTB domain-containing protein 1, RHOBTB1, KIAA0740
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
23221
ELISA
2G6
Unconjugated
RHOBTB2
Liquid
RHOBTB2
RHOBTB2 (AAH34917, 510 a.a. ∽ 619 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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