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DCK Mouse anti-Human, Clone: 2F10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA518705

Catalog No. PIMA518705


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Description

Description

Peptide Sequence: WMNNQFGQSL ELDGIIYLQA TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE DFKDKYESLV EKVKEFLSTL

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Specifications

Specifications

DCK
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
P27707
Deoxycytidine kinase; dCK
Mouse
IgG2b, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1633
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
2F10
Unconjugated
DCK
Liquid
DCK
DCK (NP_000779, 161 a.a. ∽ 260 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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