DCK Mouse anti-Human, Clone: 2F10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA518705
Peptide Sequence: WMNNQFGQSL ELDGIIYLQA TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE DFKDKYESLV EKVKEFLSTLDeoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
|PBS with no preservative; pH 7.4|
|Deoxycytidine kinase; dCK|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|DCK (NP_000779, 161 a.a. ∽ 260 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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