DCK Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527787
PA5-27787 targets DCK in Western blot and immunohistochemistry (paraffin) applications and shows reactivity with Human and Rat samples. The PA5-27787 immunogen is recombit fragment corresponding to a region within amino acids 1 and 260 of Human DCK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
|Recombit fragment corresponding to a region within amino acids 1 and 260 of Human DCK|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.025% Proclin 300; pH 7|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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