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DCK Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527787

Catalog No. PIPA527787


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Description

Description

PA5-27787 targets DCK in Western blot and immunohistochemistry (paraffin) applications and shows reactivity with Human and Rat samples. The PA5-27787 immunogen is recombit fragment corresponding to a region within amino acids 1 and 260 of Human DCK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Specifications

Specifications

DCK
Polyclonal
Unconjugated
DCK
Liquid
DCK
Recombit fragment corresponding to a region within amino acids 1 and 260 of Human DCK
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin), Western Blot
1.67 mg/mL
PBS with 20% glycerol and 0.025% Proclin 300; pH 7
P27707, P48769
deoxynucleoside kinase
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1633, 79127
Documents
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