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Dehydroepiandrosterone Sheep anti-Chemical, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA175101

Catalog No. PIPA175101


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Description

Description

PA1-75101 specifically detects Dehydroepiandrosterone. PA1-75101 has been successfully used in ELISA applications. The PA1-75101 immunogen is DHEA(17)-BTG.

Dehydroepiandrosterone (DHEA) is a natural steroid hormone produced from cholesterol by the adrenal glands. DHEA is also produced in the gonads, adipose tissue and the brain. DHEA is structurally similar to, and is a precursor of, androstenedione, testosterone, estradiol, estrone and estrogen. It is the most abundant hormone in the human body. Most of DHEA is sulfated (dehydroepiandrosterone sulfate- DEHAS) before secretion. DHEAS is the sulfated version of DHEA; - this conversion is reversibly catalyzed by sulfotransferase (SULT2A1) primarily in the adrenals, the liver, and small intestines. In blood, most DHEA is found as DHEAS with levels that are about 300 times higher than free DHEA. Blood measurements of DHEAS/DHEA are useful to detect excess adrenal activity as seen in adrenal cancer or hyperplasia, including certain forms of congenital adrenal hyperplasia. Women with polycystic ovary syndrome tend to have normal or mildly elevated levels of DHEAS. [National Center for Biotechnology Information. PubChem Compound Database; CID=5881]
Specifications

Specifications

Dehydroepiandrosterone
Polyclonal
PBS with 0.09% sodium azide
DHEA; PRASTERONE; Dehydroisoandrosterone; Androstenolone; C19H28O2
DHEA(17)-BTG
Purified
RUO
Antibody
Polyclonal
ELISA
Unconjugated
Liquid
Sheep
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
Chemical
Documents
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