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DENND1B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523885

Catalog No. PIPA523885


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Description

Description

This antibody is predicted to react with mouse based on sequence homology.

Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery.
Specifications

Specifications

DENND1B
Polyclonal
Unconjugated
DENND1B
Liquid
DENND1B
KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q6P3S1
C1ORF18, C1orf218, FAM31B, DENN domain-containing protein 1B, connecdenn 2, family with sequence similarity 31, member B
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
163486
Documents
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