DENND1B Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523885
This antibody is predicted to react with mouse based on sequence homology.Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery.
|KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B|
|Antigen Affinity Chromatography, Protein A|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|C1ORF18, C1orf218, FAM31B, DENN domain-containing protein 1B, connecdenn 2, family with sequence similarity 31, member B|
|-20° C, Avoid Freeze/Thaw Cycles|
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