MilliporeSigma anti-DFHR Clone: 2B10,
Mouse Monoclonal Antibody
Manufacturer: MilliporeSigma ST1711100UG
Specifically detects DFHR Clone: 2B10 in Human, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immuno BlottingDihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.
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|In PBS, pH 7.2.|
|Recognizes the ∽20-22kDa DHFR protein in HeLa and PC-12 cells.|
|ELISA, Immuno Blotting, Immunoblot, Immunocytochemistry|
|A recombinant polypeptide corresponding to amino acids of 88-188 human DHFR, expressed as a GST fusion protein|
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