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MilliporeSigma™ anti-DFHR Clone: 2B10, Available on GSA/VA Contract for Federal Government customers only.

Mouse Monoclonal Antibody

Manufacturer:  MilliporeSigma™ ST1711100UG

Catalog No. ST1711100UG


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Description

Description

Specifically detects DFHR Clone: 2B10 in Human, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immuno Blotting

Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia.

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Specifications

Specifications

DFHR
2B10
In PBS, pH 7.2.
Murine
IgG2a
RUO
Primary
Recognizes the ∽20-22kDa DHFR protein in HeLa and PC-12 cells.
ELISA, Immuno Blotting, Immunoblot, Immunocytochemistry
Unconjugated
Purified
A recombinant polypeptide corresponding to amino acids of 88-188 human DHFR, expressed as a GST fusion protein
100μg
−20°C
Monoclonal
Human, Rat
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