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DGAT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA116985

Catalog No. 01-670-138



Description

Description

This antibody is not applicable for IHC-paraffin embedded sections. Suggested positive control: HepG2 lysate.

Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.
Specifications

Specifications

DGAT1
Polyclonal
Unconjugated
DGAT1
Liquid
DGAT1, DGAT1A
Synthetic peptide corresponding to residues 200-300 of human DGAT1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat, Zebrafish
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q8MK44, O75907, Q9Z2A7, Q9ERM3
Acyl coenzyme A, Diacylglycerol O-acyltransferase 1, EC 2.3.1.20, Diglyceride acyltransferase, ACT-related gene product 1
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
13350, 282609, 325875, 84497, 8694
Documents
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