DHCR24 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA512457

Catalog No. PIPA512457

Description

This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology.

DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in DHCR24 gene have been associated with desmosterolosis. Also, reduced expression of DHCR24 gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

Specifications

• Antigen: DHCR24
• Classification: Polyclonal
• Gene: DHCR24
• Gene Alias: Diminuto/dwarf1 homolog; Seladin-1; 3-beta-hydroxysterol delta-24-reductase; 24-dehydrocholesterol reductase; DHCR24; KIAA0018
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 1718
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q15392
• Gene Symbols: DHCR24
• Immunogen: KLH conjugated synthetic peptide between 218-246 amino acids from the central region of human DHCR24
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG