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DHH Mouse anti-Human, Clone: 2G5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521835

Catalog No. PIMA521835


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Description

Description

Peptide Sequence: SGERKGLREL HRGDWVLAAD ASGRVVPTPV LLFLDRDLQR RASFVAVETE WPPRKLLLTP WHLVFAARGP APAPGDFAPV FARRLRAGDS VLAPGGDALR P*

This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
Specifications

Specifications

Dhh
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
O43323
GDXYM, HHG-3, SRXY7, desert hedgehog homolog, desert hedgehog protein, mutant desert hedgehog
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
50846
ELISA, Western Blot
2G5
Unconjugated
DHH
Liquid
DHH
DHH (NP_066382, 210 a.a. ∽ 310 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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