Dicer Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523088
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.DICER1 is a ribonuclease that has been extensively shown to be related to cancer. Small interfering RNAs are generated through DICER, and seem to play important roles in mitosis in normal cells and oncogenesis in mutated cells. DICER1 mutations are associated with blastoma, breast cancer, adenocarcinoma, and pancreatitis. In vision and hearing, DICER1 has been implicated in serious microRNA induced malformations of critical sensory cells. DICER1 is important in myelination and other nervous system protections. Finally, DICER1 is related to cardiovascular diseases, since microRNAs are aberrantly expressed in some pathological conditions.
|A synthetic peptide made to an internal region of the human DICER1 protein (within residues 1100-1300).|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|PBS with 0.1% BSA, 50% glycerol and 0.05% sodium azide|
|DCR1, Dicer, HERNA, MNG1, Dicer1, Dcr-1 homolog, K12H4.8-LIKE, dicer 1, double-stranded RNA-specific endoribonuclease, endoribonuclease Dicer, helicase MOI, helicase with RNAse motif, helicase-moi|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok