DKK1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523187
DescriptionDKK1 is a 266 amino acid secreted protein with two cysteine rich regions and belonging to the dickkopf family. It is involved in embryonic development through its inhibition of the WNT signaling pathway and in the reentry into the cell cycle of human adult stem cells from bone marrow. Its loss of expression plays a role in development or progression of maligt melanoma. It decreases melanocyte function and is a key player in multiple myeloma bone disease. It is a potential prognostic and diagnostic marker for breast cancer patients with poor prognosis.
|Synthetic peptide (167 GYSRRTTLSSKMYHTKGQEGSVC 185) of DKK1 protein.|
|PBS with 0.2% gelatin and 0.05% sodium azide|
|UNQ492/PRO1008, DKK-1, SK, dickkopf related protein-1, dickkopf-1 like, dickkopf-related protein 1, hDkk-1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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