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DMAP1 Rabbit anti-Bovine, Canine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523214

Catalog No. PIPA523214


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Description

Description

DNA methyltransferase 1-associated protein 1 (DMAP1) is involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The protein also specifically potentiates DAXX-mediated repression of glucocorticoid receptor-dependent transcription. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. DMAP1 is found in a wide variety of living organisms from yeasts to humans. The human DMAP1 gene is localized on chromosome 1p34.
Specifications

Specifications

DMAP1
Polyclonal
Unconjugated
DMAP1
Liquid
DMAP1
Synthetic peptide (275 ADTTAEQRRTERKAPKKK 292) of DMAP1 protein.
Protein G
RUO
Antibody
Polyclonal
Bovine, Canine, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9NPF5, Q9JI44
RP5-891H21.2, DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4, DNA methyltransferase 1-associated protein 1, DNMT1 associated protein 1, DNMT1-associated protein 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
298447, 475385, 508127, 55929, 66233
Documents
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