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DNA-PK Rabbit anti-Hamster, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA184583

Catalog No. PA184583


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Description

Description

Heat-mediated antigen retrieval using an antigen unmasking fluid is recommended, followed by a 2-hr incubation with primary antibody. Rabbit anti DNA PKcs antibody recognizes the human DNA-dependent protein kinase catalytic subunit, also known as DNA-PKcs, DNPK1 or p460.

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku ., which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
Specifications

Specifications

DNA-PK
Polyclonal
whole serum with 0.09% sodium azide
P78527, P97313
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350
Rabbit
IgG
RUO
Antibody
Polyclonal
Hamster, Human, Mouse, Rat
Gel Shift, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
PRKDC
Liquid
PRKDC
Human DNA-PKcs fragment.
100 μL
4°C or -20°C if preferred
Primary
100770748, 19090, 360748, 5591
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