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POLR2A Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528087

Catalog No. PIPA528087


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Description

Description

PA5-28087 targets DNA polymerase IIA in WB applications and shows reactivity with Human samples. The PA5-28087 immunogen is synthetic peptide corresponding to a region within amino acids 1805 and 1899 of Human DNA polymerase IIA. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Specifications

Specifications

POLR2A
Polyclonal
Unconjugated
POLR2A
Liquid
POLR2A
Synthetic peptide corresponding to a region within amino acids 1805 and 1899 of Human DNA polymerase IIA
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
0.72 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P24928
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, RNA polymerase II subunit B1, RNA-directed
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5430
Documents
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