DNMT3A, Mouse, MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human DNMT3A protein.

Manufacturer: Abnova Corporation H00001788B01

Catalog No. 89-018-898

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    Format Liquid
    Formulation No additive
    Gene DNMT3A
    Gene Accession No. NM_022552.3
    Gene Alias DNMT3A2, M.HsaIIIA
    Gene Symbols DNMT3A
    Applications Immunofluorescence,Western Blotting
    Species Reactivity Human
    Gene ID (Entrez) 1788
    Description DNA (cytosine-5-)-methyltransferase 3 alpha
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Antigen DNMT3A
    Host Species Mouse
    Immunogen DNMT3A (NP_072046.2, 1aa ∽ 912aa) full-length human protein
    Quantity 50μL
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Conjugate Unlabeled
    Cross Reactivity Human

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq


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