DNMT3A Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA511158
This antibody is predicted to react with chicken, mouse and rat based on sequence homology.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintece methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
|PBS with 0.09% sodium azide|
|DNA (cytosine-5)-methyltransferase 3A; Dnmt3a, DNA methyltransferase HsaIIIA, DNA MTase HsaIIIA, M.HsaIIIA|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 457-486 amino acids from human Dnmt3a|
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