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D4 Dopamine Receptor Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132861

Catalog No. PA132861


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Description

Description

PA1-32861 detects Dopamine receptor D4 from human samples. PA1-32861 has been successfully used in immunohistochemistry (paraffin tissue) applications. The PA1-32861 immunogen is: Synthetic peptide, KLH conjugated.

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Specifications

Specifications

D4 Dopamine Receptor
Polyclonal
Unconjugated
DRD4
Liquid
DRD4
Synthetic peptide, KLH conjugated.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.01% sodium azide; pH 7.7
P21917
D4DR
Rabbit
IgG
25 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1815
Documents
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