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Dopamine Transporter Rabbit anti-Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14656

Catalog No. PA14656


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Description

Description

This antibody is specific for the ~88 kDa DAT protein in Western blots of SDS solubilized human and mouse striatal samples and in IHC applications with formaldehyde-fixed human and monkey (Macaque) brain sections.

The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson€™s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).
Specifications

Specifications

Dopamine Transporter
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Q01959, Q61327
DAT, SLC6A3, Solute carrier family 6 member 3
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
13162, 6531
Immunohistochemistry, Western Blot
Unconjugated
SLC6A3
Liquid
SLC6A3
Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region of human SLC6A3 conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate
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