Dopamine Transporter Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14657
This antibody is specific for the ~88 kDa DAT protein in Western blots of SDS-solubilized human striatal samples and in IHC applications with formaldehyde-fixed human and monkey brain sections. Store at -20°C short term, 80°C long term.The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).
|0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5|
|DAT, SLC6A3, Solute carrier family 6 member 3|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Frozen), Western Blot|
|Synthetic peptide corresponding to amino acid residues from the extracellular loop 2 region of human SLC6A3 conjugated to KLH|
|Human, Non-human Primate|
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