Dopamine Transporter Rabbit anti-Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA184886
PA1-84886 detects a band at ~88 kDa in human caudate cell lysates. Rabbit anti Human dopamine transporter antibody recognizes an epitope within the C-terminal region of dopamine transporter (DAT), also known as solute carrier family 6.Dopamine transporter (DAT), also known as solute carrier family 6, is principally expressed in the presynaptic membrane of dopaminergic nerve terminals where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availabity of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine. The re-uptake of dopamine by the DAT is inhibited by psychostimulants such as cocaine and amphetamine.
|0.01M HEPES with 0.01% BSA, 0.15M NaCl, 50% glycerol and 0.09% sodium azide; pH 7.5|
|4°C or -20°C if preferred|
|Immunohistochemistry (Frozen), Western Blot|
|Synthetic peptide corresponding to the c-terminus region of human dopamine transporter conjugated to KLH.|
|Human, Mouse, Non-human primate|
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