DPP10 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14385
PA1-4385 detects DPP10 in human samples. PA1-4385 has been successfully used in Western blot procedures. By Western blot, this antibody detects a ~75 kDa protein representing DPP10. Oligermization and differential glycosylation produces other bands as observed with other DPP family members. PA1-4385 immunizing peptide corresponds to amino acid residues 521-539 of human DPP10.A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first axons; four of which localize within the LD block strongly associated with asthma.
|Synthetic peptide: L(521) K E A I L K K K I G K P E I K I L H(539)|
|Antigen affinity chromatography|
|PBS with 0.02% sodium azide|
|Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPL2, Dipeptidyl peptidase IV-related protein 3, DPRP-3|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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