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CRMP3 Mouse anti-Human, Clone: 1F5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA521089

Catalog No. PIMA521089


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Description

Description

Peptide Sequence: VTPGAGRFVP RKTFPDFVYK RIKARNRLAE IHGVPRGLYD GPVHEVMVPA KPGSGAPARA SCPGKISVPP VRNLHQSGFS LSGSQADDHI ARRTAQKIM

Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
Specifications

Specifications

CRMP3
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
O14531
Dihydropyrimidinase-related protein 4, DRP-4, Collapsin response mediator protein 3, CRMP-3, UNC33-like phosphoprotein 4, ULIP-4, DPYSL4, CRMP3, ULIP4
Mouse
IgG2b, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10570
ELISA, Immunoprecipitation, Western Blot
1F5
Unconjugated
DPYSL4
Liquid
DPYSL4
DPYSL4 (NP_006417, 461 a.a. ∽ 559 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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