down-regulator of transcription 1, TBP-binding (negative cofactor 2) (A02), Mouse anti-Human, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant DR1.
Manufacturer: Abnova Corporation H00001810A02
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeqSequence: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALK
|down-regulator of transcription 1, TBP-binding (negative cofactor 2)|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant DR1.|
|DR1 (NP_001929, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
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