down-regulator of transcription 1, TBP-binding (negative cofactor 2) (B01), Mouse anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human DR1 protein.

Supplier:  Abnova Corporation H00001810B01

Catalog No. 89-005-261

Description

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq

Sequence: MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI

Specifications

• Antigen: down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Classification: Polyclonal
• Description: Mouse polyclonal antibody raised against a full-length human DR1 protein.
• Gene: DR1
• Gene Alias: NC2/NC2-BETA
• Host Species: Mouse
• Quantity: 50 μL
• Research Discipline: Transcription Regulation
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Serum

• Applications: Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Formulation: No additive
• Gene Accession No.: NM_001938.2
• Gene Symbols: DR1
• Immunogen: DR1 (NP_001929.1, 1 a.a. ∼ 176 a.a) full-length human protein.
• Regulatory Status: RUO
• Whole Molecule: Yes
• Gene ID (Entrez): 1810
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.