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DR6, clone: DR-6-04-EC, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119370

Catalog No. 01-676-126


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Description

Description

CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses.

Specifications

Specifications

DR6
Monoclonal
1mg/mL
Assay Dependent
TNFRSF21
Liquid
TNFRSF21
Fusion protein representing amino acids 42-335 of human DR6 linked to the Fc portion of human IgG1.
Protein A
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunoprecipitation
DR-6-04-EC
Unconjugated
PBS with 15mM sodium azide; pH 7.4
O75509
Death receptor-6
Murine
IgG1
100μg
4° C, do not freeze, do not freeze
Primary
27242
Documents
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