DTYMK Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA513812
DescriptionThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
|PBS with 0.09% sodium azide|
|Thymidylate kinase; dTMP kinase; CDC8; TMPK; TYMK|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 164-194 amino acids from the C-terminal region of human DTYMK|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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