DUSP16 Rabbit anti-Bovine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523140
DescriptionDUSP16 is a 665 amino acid novel mitogen-activated protein kinase phosphatase belonging to the non-receptor class of the protein-tyrosine phosphatase family with a rhodanese-like domain, protein tyrosine phosphatase catalytic domain and a long terminal stretch containing nuclear export and localization signal. DUSP16 are dual-specificity phosphatases that dephosphorylate the TXY motif of MAPK TXY motifs, thereby inactivating MAP kinases. DUSP16 is ubiquitously expressed and behaves both as a nuclear shuttle and as a phosphatase. It binds to and inactivates p38 MAPK and JNK/SAPK, p38 alpha and –beta but not gamma or delta and ERK.
|Synthetic peptide (614 HEESPFEKQFKRRSC 628) of DUSP16/MKP7 protein.|
|Antigen affinity chromatography|
|Bovine, Human, Mouse, Non-human primate|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.2% gelatin and 0.05% sodium azide|
|MKP-7, MKP7, MAP kinase phosphatase 7, MAPK phosphatase-7, dual specificity protein phosphatase 16, mitogen-activated protein kinase phosphatase 7|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|618644, 70686, 80824|
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