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DUSP16 Rabbit anti-Bovine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523140

Catalog No. PIPA523140


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Description

Description

DUSP16 is a 665 amino acid novel mitogen-activated protein kinase phosphatase belonging to the non-receptor class of the protein-tyrosine phosphatase family with a rhodanese-like domain, protein tyrosine phosphatase catalytic domain and a long terminal stretch containing nuclear export and localization signal. DUSP16 are dual-specificity phosphatases that dephosphorylate the TXY motif of MAPK TXY motifs, thereby inactivating MAP kinases. DUSP16 is ubiquitously expressed and behaves both as a nuclear shuttle and as a phosphatase. It binds to and inactivates p38 MAPK and JNK/SAPK, p38 alpha and –beta but not gamma or delta and ERK.
Specifications

Specifications

DUSP16
Polyclonal
Unconjugated
DUSP16
Liquid
DUSP16
Synthetic peptide (614 HEESPFEKQFKRRSC 628) of DUSP16/MKP7 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Mouse, Non-human primate
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.2% gelatin and 0.05% sodium azide
Q9BY84
MKP-7, MKP7, MAP kinase phosphatase 7, MAPK phosphatase-7, dual specificity protein phosphatase 16, mitogen-activated protein kinase phosphatase 7
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
618644, 70686, 80824
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