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DVL1 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523409

Catalog No. PIPA523409


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Description

Description

Segment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene. DVL-1 is a cytoplasmic protein that regulates the stability of ß-catenin in the Wnt signalling pathway. DVL-1, the human homolog of the Drosophila dishevelled gene (dsh), encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes including segmentation and neuroblast specification. DVL-1 is a candidate gene for neuroblastomatous trans-formation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL-1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Specifications

Specifications

DVL1
Polyclonal
Unconjugated
DVL1
Liquid
DVL1
Synthetic peptide (84 AEGAHSDAGSQGTDSHTD 101) of DVL-1 protein.
Protein A
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O14640, P51141, Q9WVB9
RP5-890O3.5, DVL, DVL1L1, DSH homolog 1, dishevelled 1 (homologous to Drosophila dsh), dishevelled-1, segment polarity protein dishevelled homolog DVL-1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
13542, 1855, 83721
Documents
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