DVL1 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523409
DescriptionSegment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene. DVL-1 is a cytoplasmic protein that regulates the stability of ß-catenin in the Wnt signalling pathway. DVL-1, the human homolog of the Drosophila dishevelled gene (dsh), encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes including segmentation and neuroblast specification. DVL-1 is a candidate gene for neuroblastomatous trans-formation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL-1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
|Synthetic peptide (84 AEGAHSDAGSQGTDSHTD 101) of DVL-1 protein.|
|Human, Mouse, Non-human primate, Rat|
|PBS with 0.05% BSA and 0.05% sodium azide|
|O14640, P51141, Q9WVB9|
|RP5-890O3.5, DVL, DVL1L1, DSH homolog 1, dishevelled 1 (homologous to Drosophila dsh), dishevelled-1, segment polarity protein dishevelled homolog DVL-1|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|13542, 1855, 83721|
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