DTNB Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528062
PA5-28062 targets Dystrobrevin beta in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-28062 immunogen is recombit fragment corresponding to a region within amino acids 32 and 435 of Human Dystrobrevin beta. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
|Recombit fragment corresponding to a region within amino acids 32 and 435 of Human Dystrobrevin beta|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|DTN-B, beta-dystrobrevin, dystrobrevin beta|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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