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E2F2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523983

Catalog No. PIPA523983


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Description

Description

E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.
Specifications

Specifications

E2F2
Polyclonal
PBS with 0.09% sodium azide
Q14209, P56931
E2F-2, transcription factor E2F2
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1870, 242705
Western Blot
Unconjugated
E2F2
Liquid
E2F2
KLH conjugated synthetic peptide between 258-286 amino acids from the central region of human E2F2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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