EB1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA528395

Catalog No. PIPA528395

Description

PA5-28395 targets EB1 in WB applications and shows reactivity with Human samples. The PA5-28395 immunogen is recombit fragment corresponding to a region within amino acids 1 and 268 of Human EB1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.

Specifications

• Antigen: EB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q15691
• Gene Symbols: MAPRE1
• Immunogen: Recombit fragment corresponding to a region within amino acids 1 and 268 of Human EB1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 0.87 mg/mL
• Gene: MAPRE1
• Gene Alias: EB1, APC-binding protein EB1, adenomatous polyposis coli-binding protein EB1, end-binding protein 1, microtubule-associated protein RP/EB family member 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22919
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid