GPR183 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523461
DescriptionG-protein coupled receptor 183 (EBI2) belongs to the G-protein coupled receptor 1 family of proteins. It is an orphan seven-transmembrane receptor originally identified as most up-regulated gene (>200-fold) in EBV-infected cells. It plays a central role during humoral immunity. It promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. It is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also reported to be highly expressed in lung, heart and gastrointestinal tract. EBI2 deficiency in mice led to a reduction in the early antibody response to a T-dependent antigen.
|Synthetic peptide (330 SISSAVKSAPEENSRE 345) of EBI2/GPR183 protein.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|RP11-461N23.2, EBI2, EBV-induced G-protein coupled receptor 2, Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor), G-protein coupled receptor 183, epstein-Barr virus-induced G-protein coupled receptor 2|
|-20° C, Avoid Freeze/Thaw Cycles|
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