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GPR183 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523461

Catalog No. PIPA523461


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Description

Description

G-protein coupled receptor 183 (EBI2) belongs to the G-protein coupled receptor 1 family of proteins. It is an orphan seven-transmembrane receptor originally identified as most up-regulated gene (>200-fold) in EBV-infected cells. It plays a central role during humoral immunity. It promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses. It is expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. It is also reported to be highly expressed in lung, heart and gastrointestinal tract. EBI2 deficiency in mice led to a reduction in the early antibody response to a T-dependent antigen.
Specifications

Specifications

GPR183
Polyclonal
Unconjugated
GPR183
Liquid
GPR183
Synthetic peptide (330 SISSAVKSAPEENSRE 345) of EBI2/GPR183 protein.
Protein A
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P32249
RP11-461N23.2, EBI2, EBV-induced G-protein coupled receptor 2, Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor), G-protein coupled receptor 183, epstein-Barr virus-induced G-protein coupled receptor 2
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1880
Documents
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