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EDG3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA112703

Catalog No. 01-674-841


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Description

Description

Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. The couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG3 is expressed in cardiovascular, leukocyte-containing and other tissues.

A suggested positive control for this product is RH7777 cells transfected with EDG3 protein.
Specifications

Specifications

EDG3
Polyclonal
Unconjugated
S1PR3
Liquid
S1PR3
Synthetic peptide corresponding to the N terminal of EDG3 (S1P3).
Ammonium sulfate precipitation
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.08% sodium azide
Q99500
S1P3
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1903
Documents
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