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EDG6 Mouse anti-Human, FITC, Clone: 1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA112718

Catalog No. 01-674-050


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Description

Description

EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).
Specifications

Specifications

EDG6
Monoclonal
1 mg/mL
PBS with 0.08% sodium azide
O95977
S1P4
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
8698
Flow Cytometry, Western Blot
1
FITC
S1PR4
Liquid
S1PR4
Synthetic peptide corresponding to the C-terminal of EDG6 .
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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