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EFCAB4A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521059

Catalog No. PIPA521059


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Description

Description

A suggested positive control is human lung tissue lysate. PA5-21059 can be used with blocking peptide PEP-1173.

EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Specifications

Specifications

EFCAB4A
Polyclonal
Unconjugated
CRACR2B
Liquid
CRACR2B
A 15 amino acid peptide near the center of human EFCAB4A.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8N4Y2, Q80ZJ8, B0BNK9
CRACR2B; CRAC channel regulator 2B; EF-hand calcium-binding domain-containing protein 4A; calcium release-activated calcium channel regulator 2B
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
213573, 283229, 309112
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