EFCAB4A Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521059
A suggested positive control is human lung tissue lysate. PA5-21059 can be used with blocking peptide PEP-1173.EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
|A 15 amino acid peptide near the center of human EFCAB4A.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|Q8N4Y2, Q80ZJ8, B0BNK9|
|CRACR2B; CRAC channel regulator 2B; EF-hand calcium-binding domain-containing protein 4A; calcium release-activated calcium channel regulator 2B|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|213573, 283229, 309112|
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