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MilliporeSigma™ anti-EGF, Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ PC08100UG

Catalog No. PC08100UG

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Specifically detects EGF Clone: in Human samples, and it is validated for Immunohistochemistry (Paraffin)

Epidermal growth factor (EGF) is an acid- and heat-stable, 53 amino acid protein of 6045 MW originally found in rodents and humans. EGF has been shown to be a potent mitogen for a variety of cell types bothin vivo andin vitro. It binds to a 170,000 dalton receptor on the surface of cells and mediates intrinsic phosphorylation of the receptor on tyrosine residues. EGF has been detected in nearly all body fluids such as urine (urogastrone) saliva, milk and platelet-rich plasma. EGF, transforming growth factor-α and vaccinia virus growth factor all bind to and activate the EGF receptor and exhibit 30-40% amino acid homology.
Specifications

Specifications

EGF
Unconjugated
purified
human EGF
100μg
2°C to 8°C
Polyclonal
Human
Immunohistochemistry (Paraffin)
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.4.
Rabbit
IgG
RUO
Primary
Recognizes the EGF protein in salivary gland tissue. Shows no reactivity with human TGFα.
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