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EGF Receptor Mouse anti-Human, PE-CF594, Clone: EGFR.1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563431

Catalog No. BDB563431


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Description

Description

The EGFR.1 monoclonal antibody specifically binds to the epidermal growth factor receptor (EGF-R). The EGF-R is a transmembrane glycoprotein ofapproximately 170 kDa that is expressed on most cells. It consists of a glycosylated extracellular domain which binds to epidermal growth factor (EGF), a transmembrane domain, and an intracellular domain with tyrosine-kinase activity essential for signal transduction. The EGF-R plays an important role in the growth and differentiation of many cellular types. Transforming growth factor α (TGFα), vaccinia virus growth factor, and related growth factors can also bind to and signal through the EGF-R.

Specifications

Specifications

EGF Receptor
EGFR.1
EGFR; ERBB; ERBB1; HER1; mENA; PIG61
Affinity Purified
IgG2b, κ
RUO
Primary
Human
Flow Cytometry
PE-CF594
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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