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eIF-4γ Mouse, Unlabeled, Clone: 40, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610536

Catalog No. BDB610536


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Description

Description

eIF-4 proteins are required for mRNA recognition and acceleration of translation during protein synthesis. This group of proteins consists of the RNA helicase, eIF-4A; the RNA-binding protein, eIF-4B; and the cap binding proteins, eIF-4E and eIF-4γ. eIF-4γ, also referred to as p220, is a 1396 amino acid polypeptide that migrates as a 220kDa. eIF-4γ has several potential glycosylation and phosphorylation sites that could account for its anomalous electrophoretic mobility. In addition, eIF-4γ is rapidly degraded in picornavirus-infected cells due to its content of multiple PEST sequences.

Specifications

Specifications

eIF-4γ
40
Unconjugated
Affinity Purified
Human eIF-4γ aa. 1217-1386
50μg
Cell Biology
Primary
Canine, Human
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
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