eIF-4γ Mouse, Unlabeled, Clone: 40, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 610536

Catalog No. BDB610536

Description

eIF-4 proteins are required for mRNA recognition and acceleration of translation during protein synthesis. This group of proteins consists of the RNA helicase, eIF-4A; the RNA-binding protein, eIF-4B; and the cap binding proteins, eIF-4E and eIF-4γ. eIF-4γ, also referred to as p220, is a 1396 amino acid polypeptide that migrates as a 220kDa. eIF-4γ has several potential glycosylation and phosphorylation sites that could account for its anomalous electrophoretic mobility. In addition, eIF-4γ is rapidly degraded in picornavirus-infected cells due to its content of multiple PEST sequences.

Specifications

• Antigen: eIF-4γ
• Classification: Monoclonal
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Immunogen: Human eIF-4γ aa. 1217-1386
• Quantity: 50 μg
• Research Discipline: Cell Biology
• Target Species: Canine, Human
• Isotype: IgG1

• Applications: Western Blot
• Clone: 40
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.