eIF-4γ Mouse, Unlabeled, Clone: 40, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 610536
eIF-4 proteins are required for mRNA recognition and acceleration of translation during protein synthesis. This group of proteins consists of the RNA helicase, eIF-4A; the RNA-binding protein, eIF-4B; and the cap binding proteins, eIF-4E and eIF-4γ. eIF-4γ, also referred to as p220, is a 1396 amino acid polypeptide that migrates as a 220kDa. eIF-4γ has several potential glycosylation and phosphorylation sites that could account for its anomalous electrophoretic mobility. In addition, eIF-4γ is rapidly degraded in picornavirus-infected cells due to its content of multiple PEST sequences.
|Human eIF-4γ aa. 1217-1386|
|Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.|
|Store undiluted at -20°C.|
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