eIF2a Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527366
PA5-27366 targets EIF2 alpha in IF and WB applications and shows reactivity with Human samples. The PA5-27366 immunogen is recombit fragment corresponding to a region within amino acids 1 and 315 of Human EIF2 alpha. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
|Recombit fragment corresponding to a region within amino acids 1 and 315 of Human EIF2 alpha|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 20% glycerol and 0.025% Proclin 300; pH 7|
|EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, eIF-2-alpha, eukaryotic translation initiation factor 2 subunit 1, eukaryotic translation initiation factor 2 subunit alpha|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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