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eIF3i Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527582

Catalog No. PIPA527582

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PA5-27582 targets EIF3 beta in IF and WB applications and shows reactivity with Human samples. The PA5-27582 immunogen is recombit fragment corresponding to a region within amino acids 66 and 325 of Human EIF3 beta. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.


Recombit fragment corresponding to a region within amino acids 66 and 325 of Human EIF3 beta
Protein A
Immunocytochemistry, Immunofluorescence, Western Blot
2 mg/mL
PBS with 40% glycerol and 0.01% thimerosal; pH 7
EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36, TGF-beta receptor-interacting protein 1, TGFbeta receptor-interacting protein 1, eIF-3-beta, eIF3 p36, eukaryotic translation initiation factor 3 subunit 2, eukaryotic translation initiation factor 3 subunit I, eukaryotic translation initiation factor 3, subuni
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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