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eIF3d Rabbit anti-Human, Mouse, Non-human primate, Rat, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523293

Catalog No. PIPA523293


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Description

Description

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
Specifications

Specifications

eIF3D
Polyclonal
Unconjugated
EIF3D
Liquid
EIF3D
Synthetic peptide (518 RVYSLPDGTFSSDEDEEE 535) of eIF3D protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat, Zebrafish
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O15371, O70194, Q6AYK8, Q6TH15
RP5-1119A7.12-003, EIF3S7, eIF3-p66, eIF3-zeta, eIF-3-zeta, eIF3 p66, eukaryotic translation initiation factor 3 subunit 7, eukaryotic translation initiation factor 3 subunit D, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa, translation initiation factor eIF3 p66 subunit
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
336498, 362952, 55944, 8664
Documents
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