eIF3g Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525261
This antibody is predicted to react with bovine, mouse, rat and Xenopus and zebrafish based on sequence homology.Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
|KLH conjugated synthetic peptide between 209-238 amino acids from the central region of human EIF3G|
|Antigen Affinity Chromatography, Protein A|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|EIF3-P42, EIF3S4, eIF3-delta, eIF3-p44, eIF-3 RNA-binding subunit, eIF-3-delta, eIF3 p42, eIF3 p44, eukaryotic translation initiation factor 3 RNA-binding subunit, eukaryotic translation initiation factor 3 subunit 4, eukaryotic translation initiation factor 3 subunit G, eukaryotic translation initiat|
|-20° C, Avoid Freeze/Thaw Cycles|
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