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eIF3i Mouse anti-Human, Clone: 3B10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA520471
Peptide Sequence: FRTERPVNSA ALSPNYDHVV LGGGQEAMDV TTTSTRIGKF EARFFHLAFE EEFGRVKGHF GPINSVAFHP DGKSYSSGGE DGYVRIHYFD PQYFEFEFEAComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
|PBS with no preservative; pH 7.4|
|EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36, TGF-beta receptor-interacting protein 1, TGFbeta receptor-interacting protein 1, eIF-3-beta, eIF3 p36, eukaryotic translation initiation factor 3 subunit 2, eukaryotic translation initiation factor 3 subunit I, eukaryotic translation initiation factor 3, subuni|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|EIF3I (NP_003748.1, 226 a.a. ∽ 325 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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