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eIF3i Mouse anti-Human, Clone: 3B10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520471

Catalog No. PIMA520471



Description

Description

Peptide Sequence: FRTERPVNSA ALSPNYDHVV LGGGQEAMDV TTTSTRIGKF EARFFHLAFE EEFGRVKGHF GPINSVAFHP DGKSYSSGGE DGYVRIHYFD PQYFEFEFEA

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Specifications

Specifications

EIF3I
Monoclonal
0.5 mg/mL
PBS with no preservative; pH 7.4
Q13347
EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36, TGF-beta receptor-interacting protein 1, TGFbeta receptor-interacting protein 1, eIF-3-beta, eIF3 p36, eukaryotic translation initiation factor 3 subunit 2, eukaryotic translation initiation factor 3 subunit I, eukaryotic translation initiation factor 3, subuni
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
8668
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
3B10
Unconjugated
EIF3I
Liquid
EIF3I
EIF3I (NP_003748.1, 226 a.a. ∽ 325 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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