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eIF4A1 Rabbit anti-Canine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523273

Catalog No. PIPA523273


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Description

Description

eIF4A1 is a 406 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family and eukaryotic initiation factor-4A subfamily with a helicase ATP-binding domain and a helicase C-terminal domain. eIF4F eukaryotic translation initiation complex is formed by the association of eIF4A1 with eIF4E and eIF4E kinase (MNK1), eIF4B, eIF4G, PABPC1. It is closely related to eIF4A2. eIF4A1 is a eukaryotic translation initiation factor involved in protein translation/synthesis where it helps in unwinding the secondary structure of RNA in the 5 ft.-UTR of mRNAs, cap recognition, and is necessary for efficient binding mRNA to the 40S small ribosomal subunit, as well as subsequent scanning for the initiator codon. Ubiquitous expression of the enzyme eIF4A1 is seen in most tissues.
Specifications

Specifications

eIF4A1
Polyclonal
Unconjugated
EIF4A1
Liquid
EIF4A1
Synthetic peptide (377 TEEDKRTLRDIETFYNTS 394) of eIF4A1 protein.
Protein A
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P60842, P60843
DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1, eukaryotic initiation factor 4A-I, eukaryotic initiation factor 4AI, eukaryotic translation initiation factor 4A
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100688577, 13681, 1973, 287436
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