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eIF5B Mouse anti-Human, Clone: 3F9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520807

Catalog No. PIMA520807


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Description

Description

Peptide Sequence: QGTPMCVPSK NFVDIGIVTS IEINHKQVDV AKKGQEVCVK IEPIPGESPK MFGRHFEATD ILVSKISRQS IDALKDWFRD EMQKSDWQLI VELKKVFE

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
Specifications

Specifications

eIF5B
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
O60841
Eukaryotic translation initiation factor 5B, Translation initiation factor IF2, IF2, FLJ10524, KIAA0741, DKFZp434I036, Translation initiation factor IF 2, eIF 5B
Mouse
IgG2a, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
9669
ELISA
3F9
Unconjugated
EIF5B
Liquid
EIF5B
EIF5B (NP_056988, 1121 a.a. ∽ 1218 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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