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ELA3A Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA528155

Catalog No. PIPA528155


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Description

Description

PA5-28155 targets ELA3A in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28155 immunogen is recombit fragment corresponding to a region within amino acids 33 and 270 of Human ELA3A. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
Specifications

Specifications

ELA3A
Polyclonal
Unconjugated
CELA3A
Liquid
CELA3A
Recombit fragment corresponding to a region within amino acids 33 and 270 of Human ELA3A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
P09093
ELA3, ELA3A, chymotrypsin-like elastase family member 3A, elastase 1, elastase 3A, pancreatic, elastase IIIA, elastase-3A, protease E
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10136
Documents
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