Endosialin Mouse anti-Human, Unlabeled, Clone: B1/35, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564993
The B1/35 monoclonal antibody specifically binds to CD248 which is also known as Endosialin, Tumor endothelial marker 1 (TEM1), and CD164 sialomucin-like 1 (CD164L1). CD248 is a heavily glycosylated, single-pass type I transmembrane protein. CD248 belongs to the Group XIV C-Type lectin family that includes CD93 and CD141/thrombomodulin. It is expressed on pericytes and stromal fibroblasts. Although the exact functions of CD248 remain to be determined, its expression is associated with angiogenesis and lymphoid tissue organization during development, as well as, with postnatal inflammation and tumor development and growth.
|Aqueous buffered solution containing ≤0.09% sodium azide|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|Endosialin; TEM1; CD164L1|
|Diploid human fibroblasts|
|Store undiluted at 4°C|
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